Description
Pulmonary surfactant-associated protein C Antibody / SFTPC | F54672-0.4ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB, IF, IHC-P
Buffer: N/A
Limitation: This Pulmonary surfactant-associated protein C antibody is available for research use only.
Purity: Antigen affinity purified
Description: This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.
Immunogen: A portion of amino acids 144-173 from the human protein was used as the immunogen for the Pulmonary surfactant-associated protein C antibody.
Storage: Aliquot the Pulmonary surfactant-associated protein C antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
