Description
PSMB1 Antibody | F54465-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse
Application: FACS, IF, IHC-P, WB
Buffer: N/A
Limitation: This PSMB1 antibody is available for research use only.
Purity: Antigen affinity purified
Description: PSMB1 is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides.
Immunogen: A portion of amino acids 214-241 from the human protein was used as the immunogen for the PSMB1 antibody.
Storage: Aliquot the PSMB1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.