PS-341 (MG-341) | 27715-2

PS-341 (MG-341) | 27715-2 | Gentaur US, UK & Europe Disrtribition

Category: Ubiquitination/Inhibitors / Activators

Application: Useful for as a potent, cell permeable proteasome inhibitor for drug discovery research.

Background: N/A

Description: PS-341 (Pyz-Phe-boroLeu) is the active ingredient in Bortezomib. PS-341 is a reversible, cell permeable, potent, and selective proteasome inhibitor (Ki=0.6 nM). It binds the catalytic site of the 26S proteasome with high affinity and specificity. Inhibits proliferation of a number of tumor cell lines (IC50=7 nM). Inhibits TNF synthesis and FGF-induced angiogenesis.

Product Type: Inhibitors/Activators

Shippement Condition: room temp.