PROX1 Antibody | F53186-0.08ML

PROX1 Antibody | F53186-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human, Mouse

Application: WB, ELISA

Buffer: N/A

Limitation: This PROX1 antibody is available for research use only.

Purity: Antigen affinity

Description: Transcription factor involved in developmental processes such as cell fate determination, gene transcriptional regulation and progenitor cell regulation in a number of organs. Plays a critical role in embryonic development and functions as a key regulatory protein in neurogenesis and the development of the heart, eye lens, liver, pancreas and the lymphatic system. Involved in the regulation of the circadian rhythm. Represses: transcription of the retinoid-related orphan receptor RORG, transcriptional activator activity of RORA and RORG and the expression of RORA/G-target genes including core clock components: ARNTL/BMAL1, NPAS2 and CRY1 and metabolic genes: AVPR1A and ELOVL3.

Immunogen: This PROX1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 444-478 amino acids from the Central region of human PROX1.

Storage: Aliquot the PROX1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.