Description
Prohibitin 2 Antibody / PHB2 | F54917-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse, Rat
Application: IHC-P, WB
Buffer: N/A
Limitation: This Prohibitin 2 antibody is available for research use only.
Purity: Antigen affinity purified
Description: PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases. It functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. It competes with NCOA1 for modulation of ER transcriptional activity and is probably involved in regulating mitochondrial respiration activity and in aging.
Immunogen: A portion of amino acids 225-255 from the human protein was used as the immunogen for the Prohibitin 2 antibody.
Storage: Aliquot the Prohibitin 2 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
