Prohibitin 2 Antibody / PHB2 | F54917-0.08ML

Prohibitin 2 Antibody / PHB2 | F54917-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human, Mouse, Rat

Application: IHC-P, WB

Buffer: N/A

Limitation: This Prohibitin 2 antibody is available for research use only.

Purity: Antigen affinity purified

Description: PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases. It functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. It competes with NCOA1 for modulation of ER transcriptional activity and is probably involved in regulating mitochondrial respiration activity and in aging.

Immunogen: A portion of amino acids 225-255 from the human protein was used as the immunogen for the Prohibitin 2 antibody.

Storage: Aliquot the Prohibitin 2 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.