Description
Profilin 2 Antibody | R31282 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse, Rat
Application: WB, IHC-P, FACS
Buffer: N/A
Limitation: This Profilin 2 antibody is available for research use only.
Purity: Antigen affinity
Description: Profilin-2 is a protein that in humans is encoded by the PFN2 gene. The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. This gene is mapped to 3q25.1. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene. Profilin-2 binds to actin and affects the structure of the cytoskeleton. At high concentrations, it prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
Immunogen: An amino acid sequence from the C-terminus of human PFN2 (NKKAYSMAKYLRDSGF) was used as the immunogen for this Profilin 2 antibody (100% homologous in human, mouse and rat).
Storage: After reconstitution, the Profilin 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.
