Pro-MCH Antibody / PMCH | F54416-0.4ML

Pro-MCH Antibody / PMCH | F54416-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human, Mouse

Application: WB, FACS, IHC-P

Buffer: N/A

Limitation: This Pro-MCH antibody is available for research use only.

Purity: Antigen affinity purified

Description: The melanin-concentrating hormone (MCH) is a cyclic neuropeptide isolated initially from salmon pituitary gland and later from rat hypothalamus (summarized by Nahon et al., 1992 [PubMed 1572663]). In mammals, MCH perikarya are confined largely to the lateral hypothalamus and zona incerta area with extensive neuronal projections throughout the brain, including the neurohypophysis. The anatomic distribution suggests a neurotransmitter or neuromodulator role for MCH in a broad array of neuronal functions directed toward the regulation of goal-directed behavior, such as food intake, and general arousal. MCH and 2 other putative neuropeptides, NEI and NGE, are encoded by the same precursor and appear colocalized in nerve cells and in many instances within the projections. The precursor is designated pro-melanin-concentrating hormone (PMCH).

Immunogen: A portion of amino acids 94-122 from the human protein was used as the immunogen for the Pro-MCH antibody.

Storage: Aliquot the Pro-MCH antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.