PRMT5 Chemiluminescent Assay Kit | 52002L

PRMT5 Chemiluminescent Assay Kit | 52002L | Gentaur US, UK & Europe Disrtribition

Category: Methyltransferase/Assay Kit

Application: Great for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications.

Background: PRMT5 is a histone methyltransferase that exhibits methylation activity toward H4-R3.

Description: The PRMT5 Direct Activity Chemiluminescent Assay Kit is designed to measure PRMT5 activity for screening and profiling applications. The key to the PRMT5 Chemiluminescent Assay Kit is a highly specific antibody that recognizes methylated R3 residue of Histone H4. With this kit, only three simple steps on a microtiter plate are required for methyltransferase detection. First, S-adenosylmethionine is incubated with a sample containing assay buffer and methyltransferase enzyme for one hour. Next, primary antibody is added. Finally, the plate is treated with an HRP-labeled secondary antibody followed by addition of the HRP substrate to produce chemiluminescence that can then be measured using a chemiluminescence reader.

Product Type: Assay Kit

Shippement Condition: -80°C