Description
Pracinostat (SB939) | 27771-3 | Gentaur US, UK & Europe Disrtribition
Category: Deacetylase/Inhibitors / Activators
Application: N/A
Background: Pracinostat (SB939) is an orally bioavailable, small-molecule histone deacetylase (HDAC) inhibitor with potential antineoplastic activity. Pracinostat inhibits HDACs, which may result in the accumulation of highly acetylated histones. It is a pan-HDAC inhibitor, inhibiting all HDAC isozymes except HDAC6 and HDAC7.
Description: Potent and oral inhibitor of histone deacetylase (HDAC), selective for class I, II and IV HDACs. SB939 shows significant antiproliferative activity against a wide variety of tumor cell lines, with high tumor exposure and efficacy in mouse models of colorectal cancer.
Product Type: Inhibitor
Shippement Condition: Room temp. (continental US) or gel packs
