PPP1R15A Polyclonal Antibody | E-AB-19394

PPP1R15A Polyclonal Antibody | E-AB-19394 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human

Host: Rabbit

Isotype: IgG

Application: IHC, ELISA

Research Area: Cancer, Cell Biology, Epigenetics and Nuclear Signaling

Background: PPP1R15A (Protein Phosphatase 1 Regulatory Subunit 15A) is a Protein Coding gene. Diseases associated with PPP1R15A include Malignant Pleural Mesothelioma. Among its related pathways are Transcriptional activity of SMAD2/SMAD3-SMAD4 heterotrimer and Activation of cAMP-Dependent PKA. GO annotations related to this gene include protein kinase binding.This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiation.

Lead Time: 7~10 days

Concentration: 1.8 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human PPP1R15A

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification: Antigen affinity purification

Dilution: IHC 1:30-1:150, ELISA 1:2000-1:10000

Conjugation: Unconjugated

Calculated Molecular Weight: N/A

Observed Molecular Weight: N/A

Clonality: Polyclonal