Description
PPAR alpha Antibody / PPARA | F54334-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: 1331CT894.186.143
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human, Mouse
Application: IHC-P, IF, FACS, WB
Buffer: N/A
Limitation: This PPARA antibody is available for research use only.
Purity: Protein G affinity
Description: Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl- 2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety (By similarity). Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2.
Immunogen: A recombinant human protein was used as the immunogen for the PPARA antibody.
Storage: Aliquot the PPARA antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
