PP11 Antibody / ENDOU / Uridylate-specific endoribonuclease | RQ6982

PP11 Antibody / ENDOU / Uridylate-specific endoribonuclease | RQ6982 | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: WB, IHC-P, IF, FACS, Direct ELISA

Buffer: Lyophilized from 1X PBS with 2% Trehalose

Limitation: This Uridylate-specific endoribonuclease antibody is available for research use only.

Purity: Antigen affinity purified

Description: Endonuclease, poly(U) specific is a protein that in humans is encoded by the ENDOU gene. This gene encodes a protein with endoribonuclease activity that binds polyuridine-enriched single-stranded RNA. This gene was initially characterized based on its high expression in placenta but was mischaracterized as a serine protease. In mouse, this gene promotes tolerance to self-antigens by regulating B cell activation-induced cell death (AICD). The protein may be useful as a tumor marker. Multiple alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene.

Immunogen: Recombinant human protein (amino acids K20-T386) was used as the immunogen for the Uridylate-specific endoribonuclease antibody.

Storage: After reconstitution, the Uridylate-specific endoribonuclease antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.