Description
POU2AF1 Antibody / BOB-1 | V3902SAF-100UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free
Format: Purified
Clone: BOB1/2424
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: FACS, IF, WB, IHC-P
Buffer: N/A
Limitation: This BOB-1 antibody is available for research use only.
Purity: Protein G affinity
Description: BOB-1, also called POU2AF1, expression in a variety of established B-cell lines, representing different stages of B-cell development, has suggested a constitutive, B-cell-specific expression pattern. LP cells in nodular lymphocyte predominant Hodgkin lymphoma, because they are germinal center-derived, are consistently immuno-positive for BOB-1. Conversely, only some cases of classical Hodgkin lymphoma show BOB-1 immuno-reactivity within the Hodgkin and Reed-Sternberg cells. Expression of BOB-1 has been reported in follicular center cell lymphoma, diffuse large B-cell lymphoma and some cases of acute myeloid leukemia. B-CLL, marginal zone lymphoma, and mantle cell lymphoma may show weak to moderate immunoreactivity.
Immunogen: A portion of amino acids 148-255 from the human protein was used as the immunogen for the BOB-1 antibody.
Storage: Store the BOB-1 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).
