Podocalyxin Antibody / PODXL | V3917SAF-100UG

Podocalyxin Antibody / PODXL | V3917SAF-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free

Format: Purified

Clone: PODXL/2185

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: IHC-P

Buffer: N/A

Limitation: This Podocalyxin antibody is available for research use only.

Purity: Protein G affinity

Description: Podocalyxin/PODXL is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology.

Immunogen: A portion of amino acids 310-447 from the human protein was used as the immunogen for the Podocalyxin antibody.

Storage: Store the Podocalyxin antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).