Description
Podocalyxin Antibody / PODXL | V2792SAF-100UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free
Format: Purified
Clone: 2A4
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human, Rat
Application: WB, IHC-P
Buffer: N/A
Limitation: This Podocalyxin antibody is available for research use only.
Purity: PEG precipitation
Description: Podocalyxin/PODXL is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology.
Immunogen: A recombinant protein fragment containing the intracellular, transmembrane, and part of the extracellular domain of human PODXL was used as the immunogen for the Podocalyxin antibody.
Storage: Store the Podocalyxin antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).
