PNP Antibody / Inosine phosphorylase / Purine nucleoside phosphorylase | RQ6353

PNP Antibody / Inosine phosphorylase / Purine nucleoside phosphorylase | RQ6353 | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water

Format: Purified

Clone: 7G5

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: WB, IHC-P, IF

Buffer: Lyophilized from 1X PBS with 2% Trehalose

Limitation: This PNP antibody is available for research use only.

Purity: Antigen affinity purified

Description: The PNP gene encodes purine nucleoside phosphorylase, an enzyme that catalyzes the reversible phosphorolysis of the purine nucleosides and deoxynucleosides inosine, guanosine, deoxyinosine, and deoxyguanosine. It is presented results from gene dosage studies consistent with assignment of the PNP locus to band 14q13. PNP is expressed in most tissues, with markedly greater expression in lymphoid tissues. Genetic deficiencies of PNP result in severely compromised T?lymphocyte function and neurologic dysfunction.

Immunogen: Amino acids AMSDAYDRTMRQRALSTWKQMGEQRELQE were used as the immunogen for the PNP antibody.

Storage: After reconstitution, the PNP antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.