Description
PMEL17 / Melanoma gp100 Antibody | V3916-20UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Format: Purified
Clone: MSSG95-2
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: IHC-P
Buffer: N/A
Limitation: This Melanoma gp100 antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: PMEL17/Melanoma gp100/SILV plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity. [UniProt]
Immunogen: A portion of amino acids 376-502 from the human protein was used as the immunogen for the Melanoma gp100 antibody.
Storage: Store the Melanoma gp100 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).
