Description
PLPro (723-1037), His-tag (SARS-CoV-1) | 81091 | Gentaur US, UK & Europe Disrtribition
Category: Ubiquitination/Deubiquitylating Enzymes
Application: This enzyme is active in the Ub-CHOP and ISG15-CHOP assay. Suggested Substrate: Ubiquitin-Rhodamine.
Background: To date, five human coronaviruses (CoV) have been identified including severe acute respiratory syndrome (SARS).The SARS epidemic of 2002/ 2003 spread to more than 30 countries and had fatality rate of nearly 10%. The SARS genome encodes a number of proteases including papain like protease (PLpro) . Initially, it was reported that SARS PLpro was a deubiquitylase, however subsequent work has shown that PLpro is preferentially a deISGylase. PLpro cleaves ISG15-PLA2 and Ub-PLA2 with high and low efficiency respectively.
Description: SARS Coronavirus PLPro recombinant protein, with His-tag, expressed in E. coli.
Product Type: Protein
Shippement Condition: -80°C
