Platelet Derived Growth Factor Receptor beta Antibody (PDGFRB) | F50659-0.08ML

Platelet Derived Growth Factor Receptor beta Antibody (PDGFRB) | F50659-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: IHC, IF, FACS, WB, ELISA

Buffer: N/A

Limitation: This PDGFR beta antibody is available for research use only.

Purity: Purified

Description: PDGFRB is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. The gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses the gene to that of the translocation, ETS, leukemia gene, results in chronic myelomonocytic leukemia.

Immunogen: A portion of amino acids 40-72 from the human protein was used as the immunogen for this CD140b / PDGFR beta antibody.

Storage: Store at 4oC for up to one month. For long term, aliquot the PDGFR beta antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.