Description
Platelet Derived Growth Factor Receptor beta Antibody (PDGFRB) | F40302-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: 275CT1
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Mouse
Application: WB, ELISA
Buffer: N/A
Limitation: This PDGFR antibody is available for research use only.
Purity: Purified
Description: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq].
Immunogen: This PDGFR antibody was produced from a mouse immunized with recombinant protein.
Storage: Aliquot the PDGFR antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
