Description
Platelet Derived Growth Factor Receptor alpha Antibody (PDGFRA) | F50656-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB, IHC, ELISA
Buffer: N/A
Limitation: This PDGFR alpha antibody is available for research use only.
Purity: Antigen affinity
Description: PDGFRA is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes.
Immunogen: A portion of amino acids 740-769 from the human protein was used as the immunogen for this PDGFR alpha antibody.
Storage: Aliquot the PDGFR alpha antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
