PKC zeta Polyclonal Antibody | E-AB-32609

PKC zeta Polyclonal Antibody | E-AB-32609 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Isotype: IgG

Application: WB, IHC-p, IF, ELISA

Research Area: Cancer, Signal Transduction

Background: This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Phosphorylates 'Ser-311' of RELA subunit of NF-kappa-B.PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. Subunit of a quaternary complex that plays a central role in epithelial cell polarization.

Lead Time: 7~10 days

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthesized peptide derived from human PKC ζ around the non-phosphorylation site of Thr560.

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

Purification: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000

Conjugation: Unconjugated

Calculated Molecular Weight: 68 kDa

Observed Molecular Weight: 80 kDa

Clonality: Polyclonal