Description
PKC zeta Polyclonal Antibody | E-AB-32609 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human, Mouse, Rat, Monkey
Host: Rabbit
Isotype: IgG
Application: WB, IHC-p, IF, ELISA
Research Area: Cancer, Signal Transduction
Background: This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Phosphorylates 'Ser-311' of RELA subunit of NF-kappa-B.PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. Subunit of a quaternary complex that plays a central role in epithelial cell polarization.
Lead Time: 7~10 days
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthesized peptide derived from human PKC ζ around the non-phosphorylation site of Thr560.
Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Dilution: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000
Conjugation: Unconjugated
Calculated Molecular Weight: 68 kDa
Observed Molecular Weight: 80 kDa
Clonality: Polyclonal
