Description
PKCγ (PKCgamma), GST-tag | 40160 | Gentaur US, UK & Europe Disrtribition
Category: Kinase-Serine/Threonine/Protein
Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling
Background: PKCγ is a member of the protein kinase C (PKC) family of serine- and threonine-specific protein kinases that can phosphorylate a wide variety of protein targets known to be involved in diverse cellular signaling pathways. In the brain, PKCγ is translocated to cell membranes during ischemia and is rapidly removed or degraded during the second otherwise lethal ischemic insult in preconditioned brains. This suggest that ischemic preconditioning enhances downregulation of cell signaling mediated by PKCγ and may thereby provide neuroprotection (1).
Description: Recombinant human PKCγ (PKCgamma), full length, with N-terminal GST-tag, expressed in Sf9 insect cells via a baculovirus expression system.
Product Type: Protein
Shippement Condition: -80°C
