Description
PKCα (PKCalpha), GST-tag | 40157 | Gentaur US, UK & Europe Disrtribition
Category: Kinase-Serine/Threonine/Protein
Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling
Background: PKCα (PKC alpha) is a member of the protein kinase C (PKC) family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC-alpha has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control(1). PKCα has been assigned to the chromosome region 17q22-q23.2 and has been identified as a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes (2).
Description: Recombinant human PKCα (PKCalpha), full length, GenBank Accession No. NM_002737, with N-terminal GST-tag, expressed in Sf9 insect cells via a baculovirus expression system. MW= 103 kDa.
Product Type: Protein
Shippement Condition: -80°C
