PKAcγ, GST-tag | 40156

PKAcγ, GST-tag | 40156 | Gentaur US, UK & Europe Disrtribition

Category: Kinase-Serine/Threonine/Protein

Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling

Background: PKA C-gamma (PKAcγ) is a third isoform of the catalytic subunit of cAMP-dependent protein kinase. It was isolated from a human testis cDNA library and was clearly derived from a gene distinct from C-alpha and C-beta and showed tissue-specific expression. Whereas at the amino acid level C-alpha and C-beta showed 93% homology, C-gamma showed only about 80% homology to both C-alpha and C-beta (1). The PRKACG gene is intronless, contains remnants of a poly(A) tail, is flanked by direct repeats, and is co-linear with the PRKACA gene(2).

Description: Recombinant human PKAcγ(catalytic subunit C-gamma of PKA), full length, with N-terminal GST-tag, expressed in Sf9 insect cells via a baculovirus expression system.

Product Type: Protein

Shippement Condition: -80°C