Description
PIP4K2 alpha Antibody / PIP4K2A | F54749-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: FACS, IHC-P, WB, IF
Buffer: N/A
Limitation: This PIP4K2 alpha antibody is available for research use only.
Purity: Antigen affinity purified
Description: Catalyzes the phosphorylation of phosphatidylinositol 5- phosphate (PtdIns5P) on the fourth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). May exert its function by regulating the levels of PtdIns5P, which functions in the cytosol by increasing AKT activity and in the nucleus signals through ING2. May regulate the pool of cytosolic PtdIns5P in response to the activation of tyrosine phosphorylation. May negatively regulate insulin- stimulated glucose uptake by lowering the levels of PtdIns5P. May be involved in thrombopoiesis, and the terminal maturation of megakaryocytes and regulation of their size.
Immunogen: A portion of amino acids 329-363 from the human protein was used as the immunogen for the PIP4K2 alpha antibody.
Storage: Aliquot the PIP4K2 alpha antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
