Description
PIN1 Antibody | F52353-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: 855CT1.7.5
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human, Mouse, Rat
Application: IHC, WB, ELISA
Buffer: N/A
Limitation: This PIN1 antibody is available for research use only.
Purity: Purified
Description: Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Displays a preference for an acidic residue N-terminal to the isomerized proline bond. Catalyzes pSer/Thr-Pro cis/trans isomerizations. Down-regulates kinase activity of BTK. Can transactivate multiple oncogenes and induce centrosome amplification, chromosome instability and cell transformation. Required for the efficient dephosphorylation and recycling of RAF1 after mitogen activation.
Immunogen: Purified His-tagged protein was used to produced this monoclonal PIN1 antibody.
Storage: Aliquot the PIN1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
