Description
PI3Kγ (p110γ/PIK3R5) Assay Kit | 79803 | Gentaur US, UK & Europe Disrtribition
Category: Kinase/Assay Kit
Application: Useful for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications.
Background: PI3Ks (Phosphatidylinositol 3-kinases) are lipid kinases that phosphorylate PIP2 (phosphatidylinositol 4,5-bisphosphate) to produce PIP3 (phosphatidylinositol 3,4,5-trisphosphate), which plays important roles in fundamental cellular activities such as cell growth, survival, migration, and metabolism. In human cancers, gain-of-function mutations of PI3Ks are found frequently, suggesting that PI3Ks are closely involved in tumorigenesis and that PI3K targeting inhibitors may be promising anticancer drug candidates.
Description: The PI3Kγ (p110γ/PIK3R5) Assay Kit is designed to measure PI3Kγ activity for screening and profiling applications, using ADP-Glo® Kinase Assay as a detection reagent.
Product Type: Assay Kit
Shippement Condition: -80°C
