PHOX2B Antibody | V4057-100UG

PHOX2B Antibody | V4057-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Format: Purified

Clone: PHOX2B/7161R

Host: Rabbit

Clonality: Recombinant Rabbit Monoclonal

Isotype: Rabbit IgG, kappa

Species Reactivity: Human

Application: IHC-P

Application Details: Immunohistochemistry (FFPE): 1-2ug/ml

Application Note: Optimal dilution of the recombinant PHOX2B antibody should be determined by the researcher.

Purity: Protein A/G affinity

Description: Paired homeobox protein 2B (PHOX2B) is a transcription factor located on chromosome 4p13, which is essential for the formation of autonomic ganglia in the autonomic nervous system. PHOX2B is expressed in neuroblastoma, brain and adrenal glands. PHOX2B deficiency can lead to susceptibility to congenital central hypoventilation syndrome (CCHS) and neuroblastoma type 2 (NBLST2).

Immunogen: A human PHOX2B partial protein was used as the immunogen for the recombinant PHOX2B antibody.

Storage: Aliquot the recombinant PHOX2B antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.

Localization: Nucleus