Phospho-SMAD4 Antibody (pT277) | F48451-0.4ML

Phospho-SMAD4 Antibody (pT277) | F48451-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: IHC, IF, DB, ELISA

Buffer: N/A

Limitation: This phospho-SMAD4 antibody is available for research use only.

Purity: Antigen affinity

Description: Common mediator of signal transduction by TGF-beta (transforming growth factor) superfamily, SMAD4 is the common SMAD (co-SMAD). It promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. It may act as a tumor suppressor.

Immunogen: This phospho-SMAD4 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pT277 of human SMAD4.

Storage: Aliquot the phospho-SMAD4 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.