Phospho-MUC1 Antibody (pT1224) | F48634-0.4ML

Phospho-MUC1 Antibody (pT1224) | F48634-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: DB, IF, ELISA

Buffer: N/A

Limitation: This phospho-MUC1 antibody is available for research use only.

Purity: Antigen affinity

Description: MUC1 is a member of the mucin family and encodes a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas.

Immunogen: This phospho-MUC1 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pT1224 of human MUC1.

Storage: Aliquot the phospho-MUC1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.