Phospho-HDAC6 (Ser22) Polyclonal Antibody | E-AB-21286

Phospho-HDAC6 (Ser22) Polyclonal Antibody | E-AB-21286 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Application: WB, IHC-p, IF, ELISA

Research Area: Cancer, Epigenetics and Nuclear Signaling, Stem Cells

Background: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin.

Lead Time: 7~10 days

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthesized peptide derived from human HDAC6 around the phosphorylation site of Ser22

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

Purification: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000

Conjugation: Unconjugated

Calculated Molecular Weight: 131 kDa

Observed Molecular Weight: 131 kDa

Clonality: Polyclonal