Phospho-EEF2K (Ser366) Polyclonal Antibody | E-AB-21142

Phospho-EEF2K (Ser366) Polyclonal Antibody | E-AB-21142 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Rat

Host: Rabbit

Isotype: IgG

Application: WB, IHC-p, ELISA

Research Area: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction

Background: This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment.

Lead Time: 7~10 days

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthesized peptide derived from human eEF2K around the phosphorylation site of Ser366

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

Purification: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000

Conjugation: Unconjugated

Calculated Molecular Weight: 82 kDa

Observed Molecular Weight: 105 kDa

Clonality: Polyclonal