Description
Phospho-EEF2K (Ser366) Polyclonal Antibody | E-AB-21142 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human, Rat
Host: Rabbit
Isotype: IgG
Application: WB, IHC-p, ELISA
Research Area: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction
Background: This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment.
Lead Time: 7~10 days
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthesized peptide derived from human eEF2K around the phosphorylation site of Ser366
Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Dilution: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000
Conjugation: Unconjugated
Calculated Molecular Weight: 82 kDa
Observed Molecular Weight: 105 kDa
Clonality: Polyclonal