Description
Phospho-CXCR4 (Ser339) Polyclonal Antibody | E-AB-21282 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human, Mouse, Rat, Monkey
Host: Rabbit
Isotype: IgG
Application: WB, IHC-p, IF, ELISA
Research Area: Cancer, Metabolism, Immunology, Microbiology, Neuroscience, Stem Cells
Background: This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Lead Time: 7~10 days
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthesized peptide derived from human Fusin around the phosphorylation site of Ser339
Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Dilution: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000
Conjugation: Unconjugated
Calculated Molecular Weight: 40 kDa
Observed Molecular Weight: 38 kDa
Clonality: Polyclonal
