Phospho-CXCR4 (Ser339) Polyclonal Antibody | E-AB-21282

Phospho-CXCR4 (Ser339) Polyclonal Antibody | E-AB-21282 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Isotype: IgG

Application: WB, IHC-p, IF, ELISA

Research Area: Cancer, Metabolism, Immunology, Microbiology, Neuroscience, Stem Cells

Background: This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Lead Time: 7~10 days

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthesized peptide derived from human Fusin around the phosphorylation site of Ser339

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

Purification: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000

Conjugation: Unconjugated

Calculated Molecular Weight: 40 kDa

Observed Molecular Weight: 38 kDa

Clonality: Polyclonal