Phospho-CREB1 (Ser133) Polyclonal Antibody | E-AB-20849

Phospho-CREB1 (Ser133) Polyclonal Antibody | E-AB-20849 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Application: WB, IHC-p, IF, ELISA

Research Area: Cancer, Epigenetics and Nuclear Signaling, Immunology

Background: This protein binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. CREB stimulates transcription on binding to the CRE. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Implicated in synchronization of circadian rhythmicity.

Lead Time: 7~10 days

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthesized peptide derived from human CREB-1 around the phosphorylation site of Ser133

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

Purification: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:100-1:300, ELISA 1:5000-1:20000

Conjugation: Unconjugated

Calculated Molecular Weight: 37 kDa

Observed Molecular Weight: 37 kDa

Clonality: Polyclonal