Phospho c-Myc Antibody (pT58) | F48482-0.4ML

Phospho c-Myc Antibody (pT58) | F48482-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: DB, WB, ELISA

Buffer: N/A

Limitation: This phospho c-Myc antibody is available for research use only.

Purity: Antigen affinity

Description: c-Myc participates in the regulation of gene transcription. It binds DNA both in a non-specific manner and also specifically to recognizes the core sequence 5'-CAC[GA]TG-3'. This protein appears to activate the transcription of growth-related genes. Overexpression of MYC is implicated in the etiology of a variety of hematopoietic tumors. A chromosomal aberration involving MYC may be a cause of a form of B-cell chronic lymphocytic leukemia.

Immunogen: This phospho c-Myc antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pT58 of human MYC.

Storage: Aliquot the phospho c-Myc antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.