Phospho-BAD Antibody (pY110) | F48672-0.4ML

Phospho-BAD Antibody (pY110) | F48672-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: DB, ELISA

Buffer: N/A

Limitation: This phospho-BAD antibody is available for research use only.

Purity: Antigen affinity

Description: The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq].

Immunogen: This phospho-BAD antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pY110 of human BAD.

Storage: Aliquot the phospho-BAD antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.