Description
Phospho-ATF2 Antibody (pT71) | RQ5448 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: Antibody in PBS with 0.02% sodium azide and 50% glycerol
Format: Purified
Clone: FOO-1
Host Animal: Rabbit
Clonality: Rabbit Monoclonal
Species Reactivity: Human
Application: WB
Buffer: N/A
Limitation: This phospho-ATF2 antibody (pT71) is available for research use only.
Purity: Affinity purified
Description: The ATF2 gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. [RefSeq]
Immunogen: A synthetic peptide specific to human ATF2 (surrounding pT71) was used as the immunogen for the phospho-ATF2 antibody.
Storage: Store the phospho-ATF2 antibody (pT71) at -20 °C.
