Phospho-ATF2 Antibody (pT71) | RQ5448

Phospho-ATF2 Antibody (pT71) | RQ5448 | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: Antibody in PBS with 0.02% sodium azide and 50% glycerol

Format: Purified

Clone: FOO-1

Host Animal: Rabbit

Clonality: Rabbit Monoclonal

Species Reactivity: Human

Application: WB

Buffer: N/A

Limitation: This phospho-ATF2 antibody (pT71) is available for research use only.

Purity: Affinity purified

Description: The ATF2 gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. [RefSeq]

Immunogen: A synthetic peptide specific to human ATF2 (surrounding pT71) was used as the immunogen for the phospho-ATF2 antibody.

Storage: Store the phospho-ATF2 antibody (pT71) at -20 °C.