Description
PGR Polyclonal Antibody | E-AB-70121 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Application: IHC
Research Area: Cancer, Epigenetics and Nuclear Signaling, Neuroscience, Signal Transduction
Background: PGR, also named as NR3C3 and PR, belongs to the nuclear hormone receptor family and NR3 subfamily. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Progesterone receptor isoform B (PRB) is involved activation of c-SRC/MAPK signaling on hormone stimulation. The ER and PR status has been used as a predictor of breast carcinoma responsiveness to endocrine therapy and as a prognostic indicator for early recurrence.
Lead Time: 7~10 days
Concentration: 1.32 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Progesterone receptor
Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Dilution: IHC 1:200-1:800
Conjugation: Unconjugated
Calculated Molecular Weight: N/A
Observed Molecular Weight: N/A
Clonality: Polyclonal
