Description
PGK1 Antibody | F50105-0.4ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse
Application: IHC, IF, FACS, WB, ELISA
Buffer: N/A
Limitation: This PGK1 antibody is available for research use only.
Purity: Purified
Description: Also known as ATP:3-phosphoglycerate 1-phosphotransferase (EC 2.7.2.3), this major enzyme in glycolysis catalyzes the reversible conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate, generating one molecule of ATP. New blood vessel formation or angiogenesis is critical for tumor expansion and metastasis. Lay et al. (2000) showed that the plasmin reductase isolated from conditioned medium of fibrosarcoma cells is the glycolytic enzyme phosphoglycerate kinase. They concluded that phosphoglycerate kinase not only functions in glycolysis but is secreted by tumor cells and participates in the angiogenic process as a disulfide reductase.
Immunogen: A portion of amino acids 117-145 from the human protein was used as the immunogen for this PGK1 antibody.
Storage: Aliquot the PGK1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
