Description
PERK Polyclonal Antibody | E-AB-70366 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Application: WB
Research Area: Cancer, Epigenetics and Nuclear Signaling, Metabolism
Background: The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.
Lead Time: 7~10 days
Concentration: 100 μg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant protein corresponding to Mouse PERK
Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Dilution: WB 1:500-1:2000
Conjugation: Unconjugated
Calculated Molecular Weight: 140 kDa
Observed Molecular Weight: 140 kDa
Clonality: Polyclonal
