Description
PERK Polyclonal Antibody | E-AB-32546 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human
Host: Rabbit
Isotype: IgG
Application: WB, IHC-p, IF, ELISA
Research Area: Cancer, Epigenetics and Nuclear Signaling, Metabolism
Background: Phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis. Serves as a critical effector of unfolded protein response (UPR)-induced G1 growth arrest due to the loss of cyclin D1.
Lead Time: 7~10 days
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthesized peptide derived from the N-terminal region of human PERK
Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol pH 7.4.
Purification: Affinity purification
Dilution: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:40000
Conjugation: Unconjugated
Calculated Molecular Weight: 125 kDa
Observed Molecular Weight: 125 kDa
Clonality: Polyclonal
