Description
PE-Labeled Human Siglec-10 Protein, His Tag (recommended for neutralizing assay) | SI0-HP2E5-50tests| Gentaur Distribution US, UK & Europe
The siglecs (sialic acid-binding Ig-like lectins) are a distinct subset of the Ig superfamily with adhesion-molecule-like structure. We describe here a novel member of the siglec protein family that shares a similar structure including five Ig-like domains, a transmembrane domain, and a cytoplasmic tail containing two ITIM-signaling motifs. Siglec-10 was identified through database mining of an asthmatic eosinophil EST library. The Siglec-10-VAP-1 interaction seems to mediate lymphocyte adhesion to endothelium and has the potential to modify the inflammatory microenvironment via the enzymatic end products.
Source: PE-Labeled Human Siglec-10, His Tag (SI0-HP2E5) is produced via site-specific conjugation of PE to Human Siglec-10, His Tag under optimal conditions with a proprietary technology with a proprietary technology. Human Siglec-10, His Tag is expressed from human 293 cells (HEK293). It contains AA Met 17 - Thr 546 (Accession # Q96LC7-1).
Format: Liquid.
Tag: C-10×His.
Expression System: HEK293.
Expression Region: Met 17 - Thr 546.
Conjugate: PE Labeled.
Molecular Weight: 61.8 kDa.
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 61.8 kDa.
Purity: N/A.
Buffer: PBS with Arginine, pH7.4.
Storage Conditions: -70℃, aviod light.
Shipping Conditions: Dry ice
