PE/Cyanine5.5 Anti-Mouse CD54 Antibody | DL20358F-1

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SKU:
DL20358F-1
Availability:
IN STOCK
Weight:
1.00 KGS
€462.00
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Description

PE/Cyanine5.5 Anti-Mouse CD54 Antibody | DL20358F-1 | Gentaur US, UK & Europe Disrtribition

Synonyms: Intercellular adhesion molecule 1,Icam1,MALA-2,MyD10,CD54,Icam-1

Reactivity: Mouse

Host: Rat

Application: FCM

Background: CD54 is a 90 kD immunoglobulin superfamily member also known as ICAM-1 and Ly-47. It is expressed on activated endothelial cells, high endothelial venules (HEV), T and B cells, monocytes/ macrophages, granulocytes, and dendritic cells. CD54 is an important intracellular adhesion molecule that participates in T cell-T cell, T cell-B cell, and T cell-target cell interactions via binding of LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18) . CD54 has also been shown to be involved in lymphocyte trafficking, making it an important molecule in many immune reactions and inflammation. CD54 is also a receptor for rhinovirus. The YN1/1.7.4 antibody has been reported to block binding of mouse CD54 to LFA-1 and Mac-1, inhibit cell-cell adhesion, and function in antigen presentation to T cells and leukocyte migration to inflammatory tissues.

Concentration: 0.2 mg/mL

Conjugation: PE/Cyanine5.5

Buffer: PBS with 0.05% Proclin300, 1% BSA

Isotype: Rat IgG2b, κ

Storage: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

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Additional Information

Size:
25 μg
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