PDZK1 Polyclonal Antibody | E-AB-60897

PDZK1 Polyclonal Antibody | E-AB-60897 | Gentaur US, UK & Europe Disrtribition

Reactivity: Mouse

Host: Rabbit

Isotype: IgG

Application: WB

Research Area: Cancer, Metabolism, Signal Transduction

Background: This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma. Pseudogenes of this gene are located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Lead Time: 7~10 days

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant fusion protein of human PDZK1 (NP_001188254.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification: Affinity purification

Dilution: WB 1:500-1:2000

Conjugation: Unconjugated

Calculated Molecular Weight: 44 kDa/57 kDa

Observed Molecular Weight: 67 kDa

Clonality: N/A