Description
PDX1 Polyclonal Antibody | E-AB-15824 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Application: WB, IHC, ELISA
Research Area: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism, Developmental Biology, Signal Transduction, Stem Cells
Background: The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).
Lead Time: 7~10 days
Concentration: 0.4 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthetic peptide of human PDX1
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification: Affinity purification
Dilution: WB 1:500-1:2000, IHC 1:15-1:50
Conjugation: Unconjugated
Calculated Molecular Weight: 31 kDa
Observed Molecular Weight: N/A
Clonality: Polyclonal
