PDX1 Antibody (phospho-T11) | F48610-0.08ML

PDX1 Antibody (phospho-T11) | F48610-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: IF, DB, ELISA

Buffer: N/A

Limitation: This phospho-PDX1 antibody is available for research use only.

Purity: Antigen affinity

Description: PDX1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this protein are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).

Immunogen: This phospho-PDX1 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pT11 of human PDX1.

Storage: Aliquot the phospho-PDX1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.