Description
PDHB Antibody / Pyruvate Dehydrogenase E1 beta subunit | RQ5355 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: Antibody in PBS with 0.02% sodium azide and 50% glycerol
Format: Purified
Clone: AEAD-16
Host Animal: Rabbit
Clonality: Rabbit Monoclonal
Species Reactivity: Human, Mouse, Rat
Application: WB
Buffer: N/A
Limitation: This PDHB antibody is available for research use only.
Purity: Affinity purified
Description: The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and carbon dioxide, and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 beta subunit. Mutations in this gene are associated with pyruvate dehydrogenase E1-beta deficiency. [RefSeq]
Immunogen: A synthetic peptide specific to human Pyruvate Dehydrogenase E1 beta subunit / PDHB was used as the immunogen for the PDHB antibody.
Storage: Store the PDHB antibody at -20 °C.
