Description
PDGFR beta Polyclonal Antibody | E-AB-67422 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Application: IHC, IF
Research Area: Cancer, Cardiovascular, Signal Transduction
Background: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.
Lead Time: 7~10 days
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant fusion protein of human PDGFR beta (NP_002600.1).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification: Affinity purification
Dilution: IHC 1:50-1:200 IF 1:50-1:200
Conjugation: Unconjugated
Calculated Molecular Weight: N/A
Observed Molecular Weight: N/A
Clonality: N/A
