Description
PDGFR beta Antibody (CD140b) | F50659-0.4ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: IHC, IF, FACS, WB, ELISA
Buffer: N/A
Limitation: This PDGFR beta antibody is available for research use only.
Purity: Purified
Description: PDGFRB is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. The gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses the gene to that of the translocation, ETS, leukemia gene, results in chronic myelomonocytic leukemia.
Immunogen: A portion of amino acids 40-72 from the human protein was used as the immunogen for this CD140b / PDGFR beta antibody.
Storage: Store at 4oC for up to one month. For long term, aliquot the PDGFR beta antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
